Prolotherapy is also known as a non-surgical ligament and tendon reconstructive or regenerative injection therapy.

Prolotherapy has an effect on injured musculoskeletal system by stimulating the body's own self-healing mechanisms.

The method was first introduced in 1930's. Earl Gray Gedney, MD who is a surgeon himself, successfully treated his severely injured hand.

The types of prolotherapy include Dextrose Prolotherapy, Platelet Rich Plasma Prolotherapy (PRP), and adult stromal stem cell prolotherapy (Biocellular Prolotherapy) obtained from the individual’s own bone marrow or fat (adipose) tissue.


  • Joint looseness and loss of strength (lacsite)
  • Tendinitis (chronic diseases that do not heal in tendons and ligaments)
  • Bursitis (inflammation of the organs that provide lubrication for the joints and tendons and produce fluid)
  • Arthrosis (joint calcifications, wear and aging)
  • Avascular necrosis (bone necrosis due to insufficient blood flow of the osseous (bone) tissue)
  • Conditions in which muscles and tendons cannot function properly due to recurrent swelling and pain
  • Recurrent headaches
  • Recurrent neck pain
  • Recurrent back pain
  • Recurrent low back pain
  • Persistent muscle and ligament pain in the vertebral column, thoracic (rib) cage, and ribs
  • Migraine
  • Heel spur
  • Persistent pain after ankle-wrist sprains
  • Coccygodynia (coccyx pain)
  • Scoliosis (contrary to what is known in scoliosis, ligament inbalance is a very important cause) • Kyphosis
  • Kyphosis
  • Osteitis Pubis
  • Chondromalacia
  • Meniscopathy
  • Tennis elbow (epicondylitis)
  • Plantar fasciitis
  • Morton's neurinoma
  • Postoperative non-healing lumbar herniae
  • Post-operative persistent muscle, joint pain
  • Trigger points
  • Temporomandibular joint hypermobility
  • Carpal Tunel Syndrome
  • Sports injuries
  • Sciatic pain
  • Perthes disease
  • Metatarsalgia
  • Lumbago

You can find more information about Prolotheraphy in our contact page.